The Clinical AI Value Alignment lab studies artificial intelligence (AI) used in healthcare settings. We focus on algorithmic notions of interpretability, fairness, accuracy, and robustness in medical applications of AI.

The lab is part of the Computational Health Informatics Program at Boston Children’s Hospital, affiliated with Harvard Medical School.

Recent Papers

Deep Time-to-Event Models for Intrapartum Fetal Monitoring
Guilherme Seidyo Imai Aldeia, Helena Coggan, Yuting Yang, Lisa Levine, Jennifer A. McCoy, William La Cava (2026)
Preprint
A foundation-model approach to pediatric headache classification from resting-state fMRI
Guilherme Seidyo Imai Aldeia, Clara Moon, Julie M. Shulman, Navil Sethna, Allison M. Smith, Alyssa LeBel, William La Cava, Scott Holmes (2026)
Machine Learning for Healthcare Conference
A pre-train and fine-tune framework for adaptive boosting of pre-trained polygenic risk scores
Jie Hu, Raelynn Chen, Maxwell Salvatore, Olivia Wu, Okan Bilge Ozdemir, Yiwen Lu, Shawn N. Murphy, Elizabeth W. Karlson, Atlas Khan, Krzysztof Kiryluk, Iftikhar J. Kullo, Johanna L. Smith, Eimear E. Kenny, Yuan Luo, Zaldy S. Tan, William G. La Cava, Marylyn D. Ritchie, Yong Chen, Ruowang Li (2026)
Nature Communications

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